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Warfarin therapy for Medical Student OSCE

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  1. Introduce, identify, explain, consent

  2. Explain: ‘warfarin is a drug that thins your blood and makes it less likely to clot. You are taking it because you are suffering from a condition that makes you more likely to form clots’

  3. Side effects – jaundice, skin rashes, hair thinning, diarrhoea, bleeding, nausea and vomiting

  4. Toxicity – over-coagulation – look out for prolonged bleeding / blood in urine; do not take another dose and inform doctor immediately

  5. Precautions

    1. Trauma – at work and hobbies. Avoid contact sports

    2. Alcohol – excess intake may increase anticoagulant effect – have no more than 2 drinks a day

    3. Diet – avoid large changes, especially with foods containing vit K, e.g. liver and green vegetables. Cranberry and grapefruit juice.

    4. Pregnancy – warfarin dangerous especially in 1st trimester – keep GP informed

    5. Drugs

      1. Analgesia – NSAIDs not safe (ibuprofen, diclofenac), paracetamol safe

      2. Interactions

      3. OTC drugs – inform pharmacist of warfarin therapy. Do not take St John’s Wort

  6. Regular blood tests – need to test how well blood clots at regular decreasing intervals, to tailor warfarin dose

  7. INR book

    1. Check pt has one

    2. Explain: contains record of doses, clotting tests and INR. Show to any health professional treating you

  8. Additional points

    1. Bracelet – during long term treatment, in case of accident or emergency, so doctors are aware of your condition and treat accordingly

    2. Dentist – warn before any procedures

    3. Dose – at the same time each day, with or without food. If dose missed, take normal dose next day

    4. Concordance – important not to stop warfarin without seeking advice first from doctor

    5. Check for understanding

    6. Give chance for questions

    7. Offer more information in handout

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by: Admin
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Word Count: 476
Date: Fri, 22 Jan 2010 Time: 4:19 PM
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